What is a common side effect of Cisplatin?

Cisplatin is a chemotherapy drug that is widely used to treat various types of cancers. One of its notable side effects is ototoxicity, which refers to damage to the inner ear that can lead to hearing loss or balance issues. This stems from the drug's ability to accumulate in the cochlea, causing injury to the sensory hair cells that are crucial for hearing.

Ototoxicity is especially significant in patients receiving Cisplatin, as it can affect both auditory and vestibular functions and may lead to permanent hearing impairment, particularly with higher doses or prolonged use. Clinicians often monitor patients for auditory function as part of the treatment plan to address any arising issues promptly.

While there are other possible side effects associated with Cisplatin, such as peripheral neuropathy, hemorrhagic cystitis, and cardiomyopathy, these are less characteristic compared to ototoxicity. Peripheral neuropathy is more commonly associated with other chemotherapeutic agents like taxanes or vinca alkaloids, hemorrhagic cystitis is more typical with agents like cyclophosphamide, and cardiomyopathy is often linked to drugs such as anthracyclines. Therefore, ototoxicity stands out as a well-established and notable side effect of Cispl