Which psychiatric condition is associated with the highest mortality?

Anorexia nervosa is associated with the highest mortality rate among psychiatric conditions due to various factors inherent to the disorder. This condition is characterized by severe restriction of food intake, an intense fear of gaining weight, and a distorted body image, leading to significant physical health deterioration. The consequences of extreme malnutrition, electrolyte imbalances, and associated medical complications can be life-threatening. Studies have shown that the mortality rate for individuals with anorexia nervosa is markedly high compared to other psychiatric disorders, with estimates suggesting that approximately 10-20% of individuals with anorexia will die prematurely as a result of the disorder.

This heightened risk of mortality is generally attributed to both medical complications arising from the eating disorder itself, such as heart failure, and an increased risk of suicide. Anorexia nervosa often co-occurs with other mental health issues, including anxiety and depression, but its unique physiological impacts and the severity of the condition contribute significantly to its mortality statistics.