Is thrombocytosis associated with Kawasaki disease?

Thrombocytosis, which refers to an increased number of platelets in the blood, is indeed associated with Kawasaki disease. In fact, it is one of the common laboratory findings during the acute phase of the disease. Kawasaki disease primarily affects young children and is characterized by prolonged fever, rash, lymphadenopathy, and changes in the mucous membranes.

During the acute phase of Kawasaki disease, there is an inflammatory response that can lead to the activation of the bone marrow and increased production of platelets. This rise in platelet count often occurs after the initial phase of the illness and can be quite significant, sometimes reaching levels that are several times higher than normal.

Monitoring platelet levels is important in managing Kawasaki disease. If left untreated, Kawasaki disease can lead to complications such as coronary artery aneurysms, so recognizing and addressing all aspects of the disease, including thrombocytosis, is critical in pediatric care.

Understanding this connection reinforces the importance of evaluating blood counts in children presenting with signs and symptoms of Kawasaki disease, as it can assist in the diagnosis and management of this serious condition.