What additional treatment may be administered alongside urodeoxycholic acid for gallstone disease?

Urodeoxycholic acid is typically utilized in the management of gallstone disease, particularly for patients who are not candidates for surgical intervention or prefer not to undergo surgery. When considering additional treatments, analgesia, such as diclofenac, is often recommended to help manage the pain associated with gallstones.

Gallstones can lead to significant discomfort or complications, such as biliary colic or acute cholecystitis. Providing analgesia addresses the symptomatic aspect of gallstone disease, helping to alleviate pain and improve the patient's quality of life. Nonsteroidal anti-inflammatory drugs (NSAIDs), like diclofenac, are effective in reducing pain and inflammation, making them a practical choice in conjunction with urodeoxycholic acid.

While antibiotics may be necessary if there's a suspicion of an infection or if a complication arises, they are not routinely indicated in the treatment of uncomplicated gallstone disease. Chemotherapy is unrelated to gallstone treatment, as it pertains to cancer management. Surgery, on the other hand, is a definitive treatment for symptomatic gallstones, but it is not always the first line for patients who may be managed conservatively or when they are not suitable surgical candidates. Therefore, the administration of analgesia is a supportive measure that aligns