What are common symptoms of Chronic Myeloid Leukemia (CML)?

Chronic Myeloid Leukemia (CML) is a type of cancer that primarily affects the blood and bone marrow, and its symptoms often reflect the involvement of these systems. One common symptom of CML is malaise, which represents a general feeling of discomfort or uneasiness, often due to the body reacting to an underlying condition. Elevated white blood cell (WBC) count is a hallmark feature of CML and reflects the pathophysiological process of abnormal proliferation of myeloid cells. In CML, the bone marrow produces excessive amounts of these cells, which can lead to various other complications or symptoms.

The presence of malaise combined with elevated WBC is indicative of the disease's effect on the body. Knowing that CML often leads to a high white cell count is essential for diagnosis, and recognizing malaise as a symptom can help physicians consider CML when a patient presents with nonspecific symptoms and signs of hematologic abnormalities.

Other options presented do not resonate as common symptoms associated with CML. Weight gain may indicate other conditions and is not a typical symptom of leukemia. Fever can occur but is often related to infections rather than CML itself. Excessive sweating can be an associated symptom but is typically not paired with