What are the common clinical manifestations of Churg-Strauss syndrome?

Churg-Strauss syndrome, now more commonly referred to as eosinophilic granulomatosis with polyangiitis (EGPA), is characterized by a triad of symptoms that typically include asthma, vasculitis, and eosinophilia. Common clinical manifestations of the syndrome primarily involve vasculitis, which can affect multiple organ systems, including the lungs, skin, and nerves.

Pulmonary symptoms are particularly significant, as many patients experience asthma exacerbations or other respiratory issues such as pulmonary infiltrates. The vasculitis component may lead to systemic symptoms, which can include fevers, malaise, and weight loss, but the hallmark is the inflammation of blood vessels resulting in organ damage.

This is why identifying vasculitis alongside pulmonary symptoms as common manifestations provides a comprehensive understanding of the syndrome. In contrast, the other options highlight symptoms that are less specific to Churg-Strauss syndrome or do not encompass the defining characteristics of the condition. For instance, while fever and rash could occur in various conditions, they are not the hallmark indicators for EGPA. Similarly, headaches and visual disturbances or muscle weakness and hypertension can present in other diseases but do not specifically pertain to Churg-Strauss syndrome. Therefore, recognizing