What are the common signs of acute renal transplant dysfunction?

Acute renal transplant dysfunction can manifest through several clinical signs, with fluid retention and rising blood pressure being particularly indicative. When the transplanted kidney is not functioning optimally, it can lead to an accumulation of fluids in the body, which causes swelling and potentially elevates blood pressure due to increased blood volume.

This response is tied to the kidney's role in filtering excess fluid and regulating blood pressure through various mechanisms, including the renin-angiotensin-aldosterone system. When renal function declines, these mechanisms can become disrupted, resulting in the aforementioned symptoms.

Other symptoms like persistent nausea and vomiting, decreased urinary output, abdominal pain, skin rashes, and fever can occur but are not as directly correlated with acute transplant dysfunction as fluid retention and rising blood pressure are. They might indicate other issues or complications but are not primary indicators of the dysfunction itself.