What is Del Castillo Syndrome characterized by?

Del Castillo Syndrome, also known as hyperprolactinemia, is primarily characterized by galactorrhea, which is the production of breast milk not associated with childbirth or nursing, often occurring after the cessation of hormone replacement therapy. This condition arises due to an excess of prolactin in the blood, which can be triggered by various factors, including hormonal therapies.

The presence of galactorrhea is a key feature that links this syndrome to changes in hormone levels, specifically the withdrawal of hormone replacement therapy, which may lead to an imbalance that increases prolactin production. This symptom is significant in diagnosing Del Castillo Syndrome, as it directly relates to the hormonal changes occurring within the body.

Other options presented in the question, while they may be associated with different medical conditions, do not encompass the defining characteristics of Del Castillo Syndrome. Severe abdominal pain, menstrual irregularities, and increased blood pressure might pertain to various disorders or syndromes, but they do not specifically highlight the presence of hyperprolactinemia or the syndrome itself as effectively as galactorrhea does. Thus, the option identifying galactorrhea as a main characteristic is the most accurate representation of Del Castillo Syndrome.