What is the most common type of renal cell cancer found in adults?

Clear cell adenocarcinoma is recognized as the most common type of renal cell cancer found in adults, accounting for approximately 70-80% of cases. This type of carcinoma is characterized by its distinct histological features, including the presence of clear cells filled with glycogen and lipids. It typically arises from the renal tubular epithelium and is associated with specific genetic alterations, particularly in the VHL (Von Hippel-Lindau) tumor suppressor gene.

The prominence of clear cell carcinoma relative to other types makes it the primary focus in terms of diagnosis and treatment in renal cell cancer cases. Its high prevalence underscores the importance of recognizing its features and implications in clinical practice. Although there are other forms of renal cell cancer, such as papillary renal cell carcinoma, chromophobe renal cell carcinoma, and collecting duct carcinoma, they occur with significantly lower frequency.