What reaction is erythema multiforme primarily associated with?

Erythema multiforme is primarily associated with a hypersensitivity reaction, which occurs when the immune system responds excessively to an antigen. This condition is often triggered by infections, particularly viral infections such as herpes simplex virus, or by medications and other environmental factors.

In hypersensitivity reactions, the body’s immune response leads to skin lesions that can appear as red patches or target lesions, characteristic of erythema multiforme. The reaction is a result of the immune system's attempt to combat what it perceives as harmful stimuli, which leads to inflammation and the clinical manifestations seen in this condition.

Understanding this connection to hypersensitivity helps in identifying potential triggers and managing the condition effectively. While infections can precipitate erythema multiforme, it is still classified as a hypersensitivity reaction due to the nature of the immune response involved.