What symptom is not commonly associated with nephrotic syndrome?

Nephrotic syndrome is characterized by a collection of symptoms that stem from significant protein loss in the urine. This leads to a variety of systemic effects, including heavy proteinuria, low serum albumin levels, and edema.

Pitting edema occurs due to the retention of sodium and water, which is a hallmark symptom of nephrotic syndrome. Foamy urine is also commonly observed because the high levels of protein in the urine create a frothy appearance. Hypertension can develop in patients with nephrotic syndrome due to volume overload or changes in renal hemodynamics.

In contrast, hematuria, which is the presence of blood in the urine, is not typically associated with nephrotic syndrome. While hematuria may occur in other kidney disorders, it is not a defining symptom of nephrotic syndrome, which primarily involves proteinuria rather than red blood cells in the urine. This distinction is crucial for both diagnosis and understanding the underlying pathophysiology of nephrotic syndrome.