What syndrome includes parathyroid, pituitary, and pancreas tumors?

The syndrome that includes tumors of the parathyroid glands, pituitary gland, and pancreas is known as Multiple Endocrine Neoplasia Type 1, commonly referred to as MEN1. This genetic condition is characterized by a triad of endocrine tumors, specifically:

1. Parathyroid tumors: These often lead to primary hyperparathyroidism, causing hypercalcemia and related complications.

2. Pituitary tumors: These can secrete various hormones, leading to conditions such as acromegaly, Cushing's disease, or hyperprolactinemia, depending on the hormone produced.

3. Pancreatic tumors: These can include gastrinomas, insulinomas, and VIPomas, leading to various metabolic disorders.

MEN1 is inherited in an autosomal dominant pattern, and individuals with this syndrome have an increased risk of developing tumors in these endocrine glands throughout their lives. Regular monitoring and screening for these tumors are essential for early detection and management.

In contrast, other syndromes mentioned in the options do not encompass this specific combination of tumors. For example, MEN2B primarily involves medullary thyroid carcinoma and pheochromocytomas, while Marfan syndrome is a connective tissue disorder not related