What type of antibodies would be negative in an immunized Hepatitis B patient?

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In the case of an immunized Hepatitis B patient, the presence of specific antibodies can indicate the patient's immune status. When someone receives the Hepatitis B vaccine, they generate antibodies against the surface antigen of the virus, specifically anti-HBs (antibodies to Hepatitis B surface antigen). This means that a properly immunized individual will typically have positive results for anti-HBs.

The antibody anti-HBc (antibodies to Hepatitis B core antigen) is not produced as part of the vaccination response; it usually indicates previous exposure to the virus or a natural infection. As such, in an immunized individual who has not been infected with Hepatitis B, anti-HBc would be negative.

Anti-HCV (antibodies to Hepatitis C virus) is unrelated to Hepatitis B immunity and, therefore, does not affect the test results for anti-HBc or anti-HBs.

Consequently, while an immunized Hepatitis B patient will have positive anti-HBs, they will not exhibit anti-HBc, making this the correct answer in understanding the immunological response to vaccination against Hepatitis B.

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