What type of infections are associated with T cell deficiencies?

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T cell deficiencies are primarily associated with opportunistic infections due to the critical role T cells play in the immune response. T cells, especially CD4+ T helper cells, are essential for orchestrating the immune response against various pathogens, including viruses, certain bacteria, and fungi. When there is a deficiency in T cell function or number, the body's ability to fight off these opportunistic pathogens is compromised, leading to increased susceptibility.

Opportunistic infections are typically caused by organisms that do not normally cause disease in individuals with a healthy immune system, but can cause severe illness in those who are immunocompromised. This includes infections by organisms such as Pneumocystis jirovecii, certain strains of cytomegalovirus, and more unusual bacteria and fungi.

The other types of infections mentioned do not significantly correlate with T cell deficiencies. Acute bacterial infections typically involve B cells and the innate immune response. Viral infections, while relevant, encompass a broader range; T cell deficiencies do put one at risk for certain viral infections, but they are not limited to that category. Chronic inflammatory diseases are also not directly caused by T cell deficiencies, as these conditions generally involve dysregulation of immune responses rather than a lack of T cell activity.

Therefore,

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