When is the quadruple test typically done during pregnancy?

The quadruple test, also known as the quad screen, is typically performed during the second trimester of pregnancy, specifically between 15 and 18 weeks of gestation. This timing allows for the accurate measurement of specific markers in the mother’s blood, which can indicate the risk of certain congenital conditions and chromosomal abnormalities such as Down syndrome and spina bifida. The window of 15 to 18 weeks is considered optimal to ensure that the test results are both reliable and informative for further decision-making regarding the pregnancy.

Testing earlier or later than this timeframe may not yield accurate results due to lower levels of certain markers early on or the diminishing relevance of the test if conducted too late in pregnancy. The other timeframes mentioned do not align with the recommended schedule for the quadruple test, reinforcing why the 15-18 week range is the standard practice.